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Anti -GSTA1 Rabbit pAb

貨號:GB111400

品牌:Servicebio

價格:¥650

規格: 100 μl

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Product Information

 

Description GSTA1 rabbit polyclonal
Protein full name Glutathione S-transferase A1
Synonyms 13-hydroperoxyoctadecadienoate peroxidase, Androst-5-ene-3, 17-dione isomerase, GST class-alpha member 1, Gsta1, Gsta, Gstya, Glutathione S-transferase Ya, Glutathione S-transferase Ya1, Glutathione S-transferase A1, N-terminally processed
Immunogen Recombinant protein corresponding to
Mouse GSTA1
Isotype IgG
Purity Affinity purification
Predicted MW. 26 kDa
Observed MW. 26 kDa
Uniprot ID P08263, P13745, P00502

 


 

Applications

 

Applications Species Dilution Positive Tissue
WB Mouse, Rat 1: 500-1: 1000 liver, kidney

 


 

Background

This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation. Studies have shown that overexpression of GSTA1 can promote the growth of lung cancer cells, so the expression level of GSTA1 can be used to predict the degree of malignancy of lung cancer tissues. To some extent, GSTA1 is regarded as a potential lung cancer candidate targets.
 


 

Images

 

Western blot analysis of GSTA1 (GB111400)
at dilution of 1: 1000
Lane 1: Mouse liver tissue lysate
Lane 2: Mouse kidney tissue lysate
Lane 3: Rat liver tissue lysate
Lane 4: Rat kidney tissue lysate

 

Storage

 

Storage Store at -20 ℃ for one year. Avoid repeated freeze/ thaw cycles.
Storage Buffer PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. 

 


 

NOTE: This product is intended for research only.

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